The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.
Identifieur interne : 000034 ( Main/Exploration ); précédent : 000033; suivant : 000035The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.
Auteurs : Madeleine E. Sharp [États-Unis] ; Elise Caccappolo ; Helen Mejia-Santana ; Ming-X Tang ; Llency Rosado ; Martha Orbe Reilly ; Diana Ruiz ; Elan D. Louis ; Cynthia Comella ; Martha Nance ; Susan Bressman ; William K. Scott ; Caroline Tanner ; Cheryl Waters ; Stanley Fahn ; Lucien Cote ; Blair Ford ; Michael Rezak ; Kevin Novak ; Joseph H. Friedman ; Ronald Pfeiffer ; Haydeh Payami ; Eric Molho ; Stuart A. Factor ; John Nutt ; Carmen Serrano ; Maritza Arroyo ; Michael W. Pauciulo ; William C. Nichols ; Lorraine N. Clark ; Roy N. Alcalay ; Karen S. MarderSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
English descriptors
- KwdEn :
- Adult, Age of Onset, Aged, Female, Genetic Predisposition to Disease, Genetic Testing, Genotype, Heterozygote, Humans, Male, Middle Aged, Mutation (genetics), Obsessive-Compulsive Disorder (etiology), Obsessive-Compulsive Disorder (genetics), Parkinson Disease (complications), Parkinson Disease (genetics), Ubiquitin-Protein Ligases (genetics).
- MESH :
- chemical , genetics : Ubiquitin-Protein Ligases.
- complications : Parkinson Disease.
- etiology : Obsessive-Compulsive Disorder.
- genetics : Mutation, Obsessive-Compulsive Disorder, Parkinson Disease.
- Adult, Age of Onset, Aged, Female, Genetic Predisposition to Disease, Genetic Testing, Genotype, Heterozygote, Humans, Male, Middle Aged.
Abstract
Few studies have systematically investigated the association between PARKIN genotype and psychiatric co-morbidities of Parkison's disease (PD). PARKIN-associated PD is characterized by severe nigral dopaminergic neuronal loss, a finding that may have implications for behaviors rooted in dopaminergic circuits such as obsessive-compulsive symptoms (OCS).
DOI: 10.1002/mds.26065
PubMed: 25393808
Affiliations:
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Le document en format XML
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Friedman</name></author><author><name sortKey="Pfeiffer, Ronald" sort="Pfeiffer, Ronald" uniqKey="Pfeiffer R" first="Ronald" last="Pfeiffer">Ronald Pfeiffer</name></author><author><name sortKey="Payami, Haydeh" sort="Payami, Haydeh" uniqKey="Payami H" first="Haydeh" last="Payami">Haydeh Payami</name></author><author><name sortKey="Molho, Eric" sort="Molho, Eric" uniqKey="Molho E" first="Eric" last="Molho">Eric Molho</name></author><author><name sortKey="Factor, Stuart A" sort="Factor, Stuart A" uniqKey="Factor S" first="Stuart A" last="Factor">Stuart A. Factor</name></author><author><name sortKey="Nutt, John" sort="Nutt, John" uniqKey="Nutt J" first="John" last="Nutt">John Nutt</name></author><author><name sortKey="Serrano, Carmen" sort="Serrano, Carmen" uniqKey="Serrano C" first="Carmen" last="Serrano">Carmen Serrano</name></author><author><name sortKey="Arroyo, Maritza" sort="Arroyo, Maritza" uniqKey="Arroyo M" first="Maritza" last="Arroyo">Maritza Arroyo</name></author><author><name sortKey="Pauciulo, Michael W" sort="Pauciulo, Michael W" uniqKey="Pauciulo M" first="Michael W" last="Pauciulo">Michael W. Pauciulo</name></author><author><name sortKey="Nichols, William C" sort="Nichols, William C" uniqKey="Nichols W" first="William C" last="Nichols">William C. Nichols</name></author><author><name sortKey="Clark, Lorraine N" sort="Clark, Lorraine N" uniqKey="Clark L" first="Lorraine N" last="Clark">Lorraine N. Clark</name></author><author><name sortKey="Alcalay, Roy N" sort="Alcalay, Roy N" uniqKey="Alcalay R" first="Roy N" last="Alcalay">Roy N. Alcalay</name></author><author><name sortKey="Marder, Karen S" sort="Marder, Karen S" uniqKey="Marder K" first="Karen S" last="Marder">Karen S. Marder</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25393808</idno><idno type="pmid">25393808</idno><idno type="doi">10.1002/mds.26065</idno><idno type="wicri:Area/PubMed/Corpus">000344</idno><idno type="wicri:Area/PubMed/Curation">000344</idno><idno type="wicri:Area/PubMed/Checkpoint">000033</idno><idno type="wicri:Area/Ncbi/Merge">004161</idno><idno type="wicri:Area/Ncbi/Curation">004161</idno><idno type="wicri:Area/Ncbi/Checkpoint">004161</idno><idno type="wicri:Area/Main/Merge">000034</idno><idno type="wicri:Area/Main/Curation">000034</idno><idno type="wicri:Area/Main/Exploration">000034</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.</title><author><name sortKey="Sharp, Madeleine E" sort="Sharp, Madeleine E" uniqKey="Sharp M" first="Madeleine E" last="Sharp">Madeleine E. Sharp</name><affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Caccappolo, Elise" sort="Caccappolo, Elise" uniqKey="Caccappolo E" first="Elise" last="Caccappolo">Elise Caccappolo</name></author><author><name sortKey="Mejia Santana, Helen" sort="Mejia Santana, Helen" uniqKey="Mejia Santana H" first="Helen" last="Mejia-Santana">Helen Mejia-Santana</name></author><author><name sortKey="Tang, Ming X" sort="Tang, Ming X" uniqKey="Tang M" first="Ming-X" last="Tang">Ming-X Tang</name></author><author><name sortKey="Rosado, Llency" sort="Rosado, Llency" uniqKey="Rosado L" first="Llency" last="Rosado">Llency Rosado</name></author><author><name sortKey="Orbe Reilly, Martha" sort="Orbe Reilly, Martha" uniqKey="Orbe Reilly M" first="Martha" last="Orbe Reilly">Martha Orbe Reilly</name></author><author><name sortKey="Ruiz, Diana" sort="Ruiz, Diana" uniqKey="Ruiz D" first="Diana" last="Ruiz">Diana Ruiz</name></author><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D" last="Louis">Elan D. Louis</name></author><author><name sortKey="Comella, Cynthia" sort="Comella, Cynthia" uniqKey="Comella C" first="Cynthia" last="Comella">Cynthia Comella</name></author><author><name sortKey="Nance, Martha" sort="Nance, Martha" uniqKey="Nance M" first="Martha" last="Nance">Martha Nance</name></author><author><name sortKey="Bressman, Susan" sort="Bressman, Susan" uniqKey="Bressman S" first="Susan" last="Bressman">Susan Bressman</name></author><author><name sortKey="Scott, William K" sort="Scott, William K" uniqKey="Scott W" first="William K" last="Scott">William K. Scott</name></author><author><name sortKey="Tanner, Caroline" sort="Tanner, Caroline" uniqKey="Tanner C" first="Caroline" last="Tanner">Caroline Tanner</name></author><author><name sortKey="Waters, Cheryl" sort="Waters, Cheryl" uniqKey="Waters C" first="Cheryl" last="Waters">Cheryl Waters</name></author><author><name sortKey="Fahn, Stanley" sort="Fahn, Stanley" uniqKey="Fahn S" first="Stanley" last="Fahn">Stanley Fahn</name></author><author><name sortKey="Cote, Lucien" sort="Cote, Lucien" uniqKey="Cote L" first="Lucien" last="Cote">Lucien Cote</name></author><author><name sortKey="Ford, Blair" sort="Ford, Blair" uniqKey="Ford B" first="Blair" last="Ford">Blair Ford</name></author><author><name sortKey="Rezak, Michael" sort="Rezak, Michael" uniqKey="Rezak M" first="Michael" last="Rezak">Michael Rezak</name></author><author><name sortKey="Novak, Kevin" sort="Novak, Kevin" uniqKey="Novak K" first="Kevin" last="Novak">Kevin Novak</name></author><author><name sortKey="Friedman, Joseph H" sort="Friedman, Joseph H" uniqKey="Friedman J" first="Joseph H" last="Friedman">Joseph H. Friedman</name></author><author><name sortKey="Pfeiffer, Ronald" sort="Pfeiffer, Ronald" uniqKey="Pfeiffer R" first="Ronald" last="Pfeiffer">Ronald Pfeiffer</name></author><author><name sortKey="Payami, Haydeh" sort="Payami, Haydeh" uniqKey="Payami H" first="Haydeh" last="Payami">Haydeh Payami</name></author><author><name sortKey="Molho, Eric" sort="Molho, Eric" uniqKey="Molho E" first="Eric" last="Molho">Eric Molho</name></author><author><name sortKey="Factor, Stuart A" sort="Factor, Stuart A" uniqKey="Factor S" first="Stuart A" last="Factor">Stuart A. Factor</name></author><author><name sortKey="Nutt, John" sort="Nutt, John" uniqKey="Nutt J" first="John" last="Nutt">John Nutt</name></author><author><name sortKey="Serrano, Carmen" sort="Serrano, Carmen" uniqKey="Serrano C" first="Carmen" last="Serrano">Carmen Serrano</name></author><author><name sortKey="Arroyo, Maritza" sort="Arroyo, Maritza" uniqKey="Arroyo M" first="Maritza" last="Arroyo">Maritza Arroyo</name></author><author><name sortKey="Pauciulo, Michael W" sort="Pauciulo, Michael W" uniqKey="Pauciulo M" first="Michael W" last="Pauciulo">Michael W. Pauciulo</name></author><author><name sortKey="Nichols, William C" sort="Nichols, William C" uniqKey="Nichols W" first="William C" last="Nichols">William C. Nichols</name></author><author><name sortKey="Clark, Lorraine N" sort="Clark, Lorraine N" uniqKey="Clark L" first="Lorraine N" last="Clark">Lorraine N. Clark</name></author><author><name sortKey="Alcalay, Roy N" sort="Alcalay, Roy N" uniqKey="Alcalay R" first="Roy N" last="Alcalay">Roy N. Alcalay</name></author><author><name sortKey="Marder, Karen S" sort="Marder, Karen S" uniqKey="Marder K" first="Karen S" last="Marder">Karen S. Marder</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genetic Testing</term><term>Genotype</term><term>Heterozygote</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Mutation (genetics)</term><term>Obsessive-Compulsive Disorder (etiology)</term><term>Obsessive-Compulsive Disorder (genetics)</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (genetics)</term><term>Ubiquitin-Protein Ligases (genetics)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Ubiquitin-Protein Ligases</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Obsessive-Compulsive Disorder</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Mutation</term><term>Obsessive-Compulsive Disorder</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age of Onset</term><term>Aged</term><term>Female</term><term>Genetic Predisposition to Disease</term><term>Genetic Testing</term><term>Genotype</term><term>Heterozygote</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Few studies have systematically investigated the association between PARKIN genotype and psychiatric co-morbidities of Parkison's disease (PD). PARKIN-associated PD is characterized by severe nigral dopaminergic neuronal loss, a finding that may have implications for behaviors rooted in dopaminergic circuits such as obsessive-compulsive symptoms (OCS).</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region><settlement><li>New York</li></settlement><orgName><li>Université Columbia</li></orgName></list><tree><noCountry><name sortKey="Alcalay, Roy N" sort="Alcalay, Roy N" uniqKey="Alcalay R" first="Roy N" last="Alcalay">Roy N. Alcalay</name><name sortKey="Arroyo, Maritza" sort="Arroyo, Maritza" uniqKey="Arroyo M" first="Maritza" last="Arroyo">Maritza Arroyo</name><name sortKey="Bressman, Susan" sort="Bressman, Susan" uniqKey="Bressman S" first="Susan" last="Bressman">Susan Bressman</name><name sortKey="Caccappolo, Elise" sort="Caccappolo, Elise" uniqKey="Caccappolo E" first="Elise" last="Caccappolo">Elise Caccappolo</name><name sortKey="Clark, Lorraine N" sort="Clark, Lorraine N" uniqKey="Clark L" first="Lorraine N" last="Clark">Lorraine N. Clark</name><name sortKey="Comella, Cynthia" sort="Comella, Cynthia" uniqKey="Comella C" first="Cynthia" last="Comella">Cynthia Comella</name><name sortKey="Cote, Lucien" sort="Cote, Lucien" uniqKey="Cote L" first="Lucien" last="Cote">Lucien Cote</name><name sortKey="Factor, Stuart A" sort="Factor, Stuart A" uniqKey="Factor S" first="Stuart A" last="Factor">Stuart A. Factor</name><name sortKey="Fahn, Stanley" sort="Fahn, Stanley" uniqKey="Fahn S" first="Stanley" last="Fahn">Stanley Fahn</name><name sortKey="Ford, Blair" sort="Ford, Blair" uniqKey="Ford B" first="Blair" last="Ford">Blair Ford</name><name sortKey="Friedman, Joseph H" sort="Friedman, Joseph H" uniqKey="Friedman J" first="Joseph H" last="Friedman">Joseph H. Friedman</name><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D" last="Louis">Elan D. Louis</name><name sortKey="Marder, Karen S" sort="Marder, Karen S" uniqKey="Marder K" first="Karen S" last="Marder">Karen S. Marder</name><name sortKey="Mejia Santana, Helen" sort="Mejia Santana, Helen" uniqKey="Mejia Santana H" first="Helen" last="Mejia-Santana">Helen Mejia-Santana</name><name sortKey="Molho, Eric" sort="Molho, Eric" uniqKey="Molho E" first="Eric" last="Molho">Eric Molho</name><name sortKey="Nance, Martha" sort="Nance, Martha" uniqKey="Nance M" first="Martha" last="Nance">Martha Nance</name><name sortKey="Nichols, William C" sort="Nichols, William C" uniqKey="Nichols W" first="William C" last="Nichols">William C. Nichols</name><name sortKey="Novak, Kevin" sort="Novak, Kevin" uniqKey="Novak K" first="Kevin" last="Novak">Kevin Novak</name><name sortKey="Nutt, John" sort="Nutt, John" uniqKey="Nutt J" first="John" last="Nutt">John Nutt</name><name sortKey="Orbe Reilly, Martha" sort="Orbe Reilly, Martha" uniqKey="Orbe Reilly M" first="Martha" last="Orbe Reilly">Martha Orbe Reilly</name><name sortKey="Pauciulo, Michael W" sort="Pauciulo, Michael W" uniqKey="Pauciulo M" first="Michael W" last="Pauciulo">Michael W. Pauciulo</name><name sortKey="Payami, Haydeh" sort="Payami, Haydeh" uniqKey="Payami H" first="Haydeh" last="Payami">Haydeh Payami</name><name sortKey="Pfeiffer, Ronald" sort="Pfeiffer, Ronald" uniqKey="Pfeiffer R" first="Ronald" last="Pfeiffer">Ronald Pfeiffer</name><name sortKey="Rezak, Michael" sort="Rezak, Michael" uniqKey="Rezak M" first="Michael" last="Rezak">Michael Rezak</name><name sortKey="Rosado, Llency" sort="Rosado, Llency" uniqKey="Rosado L" first="Llency" last="Rosado">Llency Rosado</name><name sortKey="Ruiz, Diana" sort="Ruiz, Diana" uniqKey="Ruiz D" first="Diana" last="Ruiz">Diana Ruiz</name><name sortKey="Scott, William K" sort="Scott, William K" uniqKey="Scott W" first="William K" last="Scott">William K. Scott</name><name sortKey="Serrano, Carmen" sort="Serrano, Carmen" uniqKey="Serrano C" first="Carmen" last="Serrano">Carmen Serrano</name><name sortKey="Tang, Ming X" sort="Tang, Ming X" uniqKey="Tang M" first="Ming-X" last="Tang">Ming-X Tang</name><name sortKey="Tanner, Caroline" sort="Tanner, Caroline" uniqKey="Tanner C" first="Caroline" last="Tanner">Caroline Tanner</name><name sortKey="Waters, Cheryl" sort="Waters, Cheryl" uniqKey="Waters C" first="Cheryl" last="Waters">Cheryl Waters</name></noCountry><country name="États-Unis"><region name="État de New York"><name sortKey="Sharp, Madeleine E" sort="Sharp, Madeleine E" uniqKey="Sharp M" first="Madeleine E" last="Sharp">Madeleine E. Sharp</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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